Catheter for modification of agent formulation
AssigneeDurect Corporation
InventorsTai Chan, Tim Nelson, Jim Brown
Life of this patent
Estimating the term…
Abstract
The present invention provides a catheter for use in delivering formulation that allows modification of the formulation prior to or concomitant with its transport or at a delivery site. The catheter comprises an elongate body, which defines an inner lumen extending between the proximal and distal ends, and a modifying element, which provides for modification of one or more components of a formulation prior to or concomitant with release at the delivery site.
Claims20
1-21. (canceled)
The method of claim 28, wherein the formulation is introduced into the inlet at a low volume rate.
The method of claim 28, wherein the elongate body passageway is at least partially filled with an agent formulation prior to said implanting.
24-27. (canceled)
A method for delivery of an agent to a delivery site in a subject, the method comprising the steps of:
- (a) implanting at a delivery site in a subject at least a distal portion of a catheter comprising:
- an elongate body comprising a proximal end defining an inlet, and a distal end defining an outlet, the elongate body defining a passageway extending between the proximal and distal ends, and
- a modifying element operatively associated with the elongate body such that at least an inner wall of the modifying element is in fluid communication with the elongate body passageway;
- wherein flowable formulation introduced into the elongate body inlet moves through the elongate body passageway, contacts the modifying element inner wall, and exits the catheter;
- and
- (b) introducing a formulation comprising an agent into the inlet of the elongate body;
- wherein the introduced agent flows through the elongate body passageway, contacts an inner wall of the modifying element, and is released at the delivery site in the subject.
Dependencies are inferred from the claim text.