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US 2007/0185332 A1Published application
Process for the synthesis of imidazoles
AssigneeAllergan, Inc.
InventorsLloyd Dolby, Shervin Esfandiari, Michael Garst
Life of this patent
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Abstract
The present invention provides a process for the preparation of imidazoles by reacting a cyano compound with a silylalkylisocyanide compound. Such imidazoles are useful pharmacologically-active compounds and/or intermediates for the preparation of pharmacologically-active compounds.
Claims4
A compound having the formula
- wherein R is selected from the group consisting of aryl, alkyl, alkenyl and alkynyl radicals and substituted derivatives thereof wherein said substituted derivatives may include one or more heteroatoms selected from the group consisting of halogen, oxygen, nitrogen sulfur and phosphorus atoms;
- and
- each R2 is independently H or alkyl having from 1 to 6 carbon atoms.
Dependencies are inferred from the claim text.