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US 2007/0185330 A1Published application
Liquids
AssigneeThe University of York
InventorAdam Walker
Life of this patent
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Abstract
The present invention relates to ionic liquid comprising an anion and a cation wherein the cation is a primary, secondary or tertiary ammonium ion containing a protonated nitrogen atom.
Claims31
1-31. (canceled)
An ionic liquid comprising an anion and a cation characterized in that the cation is a secondary or tertiary nitrogen-containing cation of the formula (I)
- N+HRR′R″ (I)
- wherein:
- R is a hydrocarbyl substituted with one or more substituents selected from the group consisting of nitrile, nitro, amino, or other nitrogen-containing functional group;
- thiol;
- alkylthio;
- sulphonyl;
- thiocyanate;
- isothiocyanate;
- azido;
- hydrazine;
- halogen;
- alkyl optionally having one or more ether or thioether linkages;
- alkoxy;
- alkenyl;
- hydroxyl;
- carbonyl;
- carboxyl;
- boronate;
- silyl;
- and substituted amino;
- R′ is a hydrocarbyl optionally substituted with one or more substituents selected from the group consisting of nitrile, nitro, amino, or other nitrogen-containing functional group;
- thiol;
- alkylthio;
- sulphonyl;
- thiocyanate;
- isothiocyanate;
- azido;
- hydrazine;
- halogen;
- alkyl optionally having one or more ether or thioether linkages;
- alkoxy;
- alkenyl;
- hydroxyl;
- carbonyl;
- carboxyl;
- boronate;
- silyl;
- and substituted amino;
- R″ is H or R′;
- any two or three of R, R′ and R″ may optionally be joined together with the N to form a heterocyclic group, provided the heterocyclic group is not heteroaryl;
- the ionic liquid has a melting point below 25° C. and contains less than 1% water;
- and
- the ionic liquid is not diethanolammonium chloride.
40 more elements
A method for carrying out an enzyme-catalyzed reaction comprising:
- i.) providing a liquid reaction medium which contains an ionic liquid comprising an anion and a cation wherein the cation is a primary, secondary or tertiary ammonium ion of the formula (I)
- N+HRR′R″ (I)
- wherein:
- R is a hydrocarbyl substituted with one or more substituents selected from the group consisting of nitrile, nitro, amino, or other nitrogen-containing functional group;
- thiol;
- alkylthio;
- sulphonyl;
- thiocyanate;
- isothiocyanate;
- azido;
- hydrazine;
- halogen;
- alkyl optionally having one or more ether or thioether linkages;
- alkoxy;
- alkenyl;
- hydroxyl;
- carbonyl;
- carboxyl;
- boronate;
- silyl;
- and substituted amino;
- R′ and R″, which may be the same or different, are H or a hydrocarbyl optionally substituted with one or more substituents selected from the group consisting of nitrile, nitro, amino, or other nitrogen-containing functional group;
- thiol;
- alkylthio;
- sulphonyl;
- thiocyanate;
- isothiocyanate;
- azido;
- hydrazine;
- halogen;
- alkyl optionally having one or more ether or thioether linkages;
- alkoxy;
- alkenyl;
- hydroxyl;
- carbonyl;
- carboxyl;
- boronate;
- silyl;
- and substituted amino;
- and
- any two or three of R, R′ and R″ may be joined together with the N to form a heterocyclic (excluding heteroaryl) group;
- ii.) providing in the liquid reaction medium an enzyme and a substrate for the enzyme;
- and
- iii.) allowing reaction of the substrate to occur.
41 more elements
Dependencies are inferred from the claim text.