Nucleic acids encoding a G-protein coupled receptor involved in sensory transduction
AssigneesThe Regents of the University of California, The Government of the United States, as represented by the Secretary of the Department of, Health and Human Services
InventorsCharles Zuker, Jon Adler, Juergen Lindemeier, Nick Ryba, Mark Hoon
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Abstract
The invention provides isolated nucleic acid and amino acid sequences of sensory cell specific G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sensory cell specific G-protein coupled receptors.
Claims19
1-63. (canceled)
A recombinant cell that is transfected with an isolated nucleic acid encoding a taste transduction G-protein coupled receptor and expresses the receptor, wherein the receptor comprises an amino acid sequence having at least 80% identity to SEQ ID NO:1, SEQ ID NO:2, or SEQ ID NO:3.
Dependencies are inferred from the claim text.