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OwnerY. Liu, Jan Lau +2inventors
InventorsY. Liu, Jan Lau, John Stalcup, Michael Lyster
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One embodiment of the invention comprises a differential composite in which bone cement everywhere or substantially everywhere contains at least some non-zero volume fraction of particles, and in which the local volume fraction of particles may vary from place to place in the composite in a controlled manner. The variation may be by identifiable region or may be in the form of a gradient of the local volume fraction of particles. In at least some places, the local volume fraction of particles may be such that the particles act as crack arrestors. Close to the interface with natural bone, the local volume fraction of particles may be greater. In at least some places adjoining natural bone, the local volume fraction of particles may be such as to allow bone ingrowth into appropriate region(s) of the composite, resulting in improved interfacial shear strength. Methods and apparatuses for producing and delivering the composite are also disclosed, which may include use of an introducer and an expandable basket-type device.
A composite comprising:
A composite comprising:
A composite comprising:
A composite comprising:
A composite comprising:
A stabilized bone comprising:
A stabilized bone comprising:
A method for filling a bone cavity with a particle impregnated bone cement composite comprising:
An apparatus for delivering and depositing particles on a wall of a bone cavity, the apparatus comprising a double-umbrella basket, said double-umbrella basket configured to expand by mechanical force or pressure and when expanded releases said particles.
A method of treating a bone, comprising:
A method of treating a bone, comprising introducing within the bone a cement comprising particles, wherein said particles comprise an active pharmaceutical ingredient.
A method of creating a cavity, comprising:
A method of creating a cavity within a bone, comprising:
An apparatus for creating a cavity within a bone, comprising:
An apparatus for creating a cavity within a bone, comprising:
An apparatus for creating a cavity within a bone, comprising:
An apparatus for creating a cavity in a bone, comprising:
An apparatus for creating a cavity within a bone, comprising:
An apparatus for creating a cavity, comprising:
An apparatus for creating a cavity, comprising:
A method for treating or preventing a vertebral compression fracture comprising the steps of:
A method for treating or preventing a vertebral compression fracture comprising the steps of:
A method of treating a bone, comprising the steps of:
A method of treating or preventing vertebral compression fracture, comprising the steps of:
A kit for treatment of a vertebral compression fracture, the kit comprising:
Dependencies are inferred from the claim text.