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US 2007/0185205 A1Published application
Airway Alkalinization as Therapy for Airway Diseases
OwnerJohn Hunt, Benjamin Gastoninventors
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Abstract
The present invention relates to a method of treating asthma by raising the pH of the airways of an individual. The effect can be mediated directly by administering a pharmaceutically acceptable basic solution or alternatively, the effect can be mediated by enhancing the activity of glutaminase.
Claims6
A method for enhancing the therapeutic efficacy of inhaled S-nitrosothiols (SNO) used in the treatment of asthma and/or other airway diseases of a patient comprising
- combining at least one non-toxic, alkaline composition, selected from the group comprising acetate salts, ammonium salts, phosphate salts, bicarbonate salts, glycine and glutamine together with an acid or base component so as to result in a combination having an alkaline pKa, and
- administering the combination in an aerosol form to the airways of a patient.
Dependencies are inferred from the claim text.