Metaxalone polymorphs
AssigneeDabur Pharma Limited
InventorsJayanta Chattopadhyay, Subrata Sarkar, Jyan Mahanty, Susanta Hazra, Moloy Mitra, Manoj Singh
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Abstract
The invention provides two crystalline forms A and B of the skeletal muscle relaxant and anxiolytic agent, Metaxalone of formula (I), and a process for preparation thereof. The two crystalline forms A and B are bioavailable. The invention further provides pharmaceutical compositions comprising the two bioavailable crystalline forms, useful for the relief of discomforts associated with acute, painful musculoskeletal conditions.
Claims52
Crystalline Metaxalone Form A.
Crystalline Metaxalone Form B.
Crystalline Metaxalone Form A which is bioavailable.
Crystalline Metaxalone Form B which is bioavailable.
A pharmaceutical composition comprising crystalline Form A of Metaxalone and pharmaceutically acceptable excipients.
A pharmaceutical composition comprising crystalline Form B of Metaxalone and pharmaceutically acceptable excipients.
A method for the treatment of discomforts associated with acute, painful musculoskeletal conditions comprising administration of a pharmaceutical composition comprising crystalline Form A or Form B of Metaxalone to a patient in need thereof.
Dependencies are inferred from the claim text.