Sodium salts of 5-[4-[2-(n-methyl-n-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione
AssigneeSmithKline Beecham Corporation
InventorsAndrew CRAIG, Michael Millan
Life of this patent
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Abstract
A compound 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione sodium salt, or a pharmaceutically acceptable solvate thereof, characterised in that the sodium salt is non-hygroscopic or slightly hygroscopic; a pharmaceutical composition containing such a compound and the use of such a compound in medicine.
Claims9
A compound, which is 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione sodium salt, wherein said compound provides at least one of:
- (i) an infrared spectrum substantially in accordance with FIG. 1;
- (ii) a Raman spectrum substantially in accordance with FIG. 2;
- (iii) an X-Ray powder diffraction pattern substantially in accordance with FIG. 3;
- (iv) a solid state 13C NMR spectrum substantially in accordance with FIG. 4;
- and
- (v) a melting point in the range of from 245 to 250° C.
A compound, which is 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione sodium salt, wherein said compound provides a Raman spectrum substantially in accordance with FIG. 2.
A compound, which is 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione sodium salt, wherein said compound provides an X-Ray powder diffraction pattern substantially in accordance with FIG. 3.
Dependencies are inferred from the claim text.