Novel purine derivatives, method for preparing them, their application as medicinal products, pharmaceutical compositions and novel use

A product of formula (I):

• in which:
• Y represents N, O, S, CHR3 or ═CR3 the dashed line on the ring indicating that the corresponding bond is single or double,
• R and R1, which may be identical or different, represent hydrogen, halogen, hydroxyl, alkyl, alkoxy, cyano, NO2, NR4R5, trifluoromethyl, trifluoromethoxy, aryl, heteroaryl, —S(O)n-NR4R5, acyl, —NH—CO-alkyl or —NH—CO—NH-phenyl in which the alkyl and phenyl radicals are optionally substituted with one or more radicals chosen from thienyl and phenyl, itself optionally substituted, these phenyl radicals themselves being optionally substituted with one or more radicals chosen from halogen atoms and the radicals —NH2, —NHAlk and —N(Alk)2,
• n represents an integer of 0 to 2,
• R3 represents hydrogen, halogen, alkyl, cyano, NO2, NR4R5, trifluoromethyl, aryl,
• R2 represents a radical R4, OR4, SR4 or NR4R5 in which R4 represents a hydrogen atom or an alkyl, cycloalkyl or aryl radical,
• NR4R5 being such that either R4 and R5, which may be identical or different, are chosen from the values for R4 or R4 and R5 form, together with the nitrogen atom to which they are attached, a cyclic radical containing 4 to 6 ring members containing one or more hetero atoms, which may be identical or different, chosen from N, O and S,
• all the alkyl, alkoxy, cycloalkyl, aryl and heterocyclic radicals defined above being optionally substituted with one or more radicals chosen from halogen atoms, hydroxyl, cyano, trifluoromethyl, trifluoromethoxy, alkoxy, aryl and heterocyclic radicals, radicals with an acid or acid isostere function and the radicals —NHR4, —NalkR4, —COR4, —COOR4, CONalkR4 and —CONHR4 in which R4 has the meaning given above and alk represents an alkyl radical,
• all the aryl and heterocyclic radicals defined above also being optionally substituted with one or more alkyl, hydroxyalkyl and phenylalkyl radicals,
• all the aryl radicals defined above also being optionally substituted with a dioxol radical,
• all the alkyl and alkoxy radicals defined above being linear or branched and containing at most 6 carbon atoms,
• all the cycloalkyl radicals defined above containing at most 6 carbon atoms,
• said products of formula (I) being in all the possible racemic, enantiomeric and diastereoisomeric isomer forms, and also the pharmaceutically acceptable addition salts with inorganic and organic acids or with inorganic and organic bases of said product of formula (I).