Cancer treatment with topoisomerase-ii inhibitor, a bis-dioxypiperazine and radiation
AssigneeTopotarget A/S
InventorsKenneth Hofland, Maxwell Sehested, Paul Kristjansen, Annenette Thougaard, Peter Jensen
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Abstract
The present invention relates to a method of treatment of a tumour cell which comprises administering to a subject in need of treatment an effective amount of a topoisomerase-II poison, e.g. etoposide, in combination with a bis-dioxypiperazine, e.g. dexrazoxane wherein said subject is further treated with radiation.
Claims10
A method of treatment of a tumour cell which comprises administering to a subject in need of treatment an effective amount of a topoisomerase-II poison in combination with a bis-dioxypiperazine, wherein said subject is further treated with radiation.
A topoisomerase-II poison and a bis-dioxypiperazine, as a combined preparation for simultaneous, separate or sequential use in tumour therapy of a patient undergoing radiation treatment.
A topoisomerase-II poison, a bis-dioxypiperazine and a source of ionising radiation as a combined preparation for simultaneous, separate or sequential of the topoisomerase-II poison and bis-dioxypiperazine and separate or sequential use of the source of ionising radiation in tumour therapy.
A topoisomerase-II poison, a bis-dioxypiperazine and ionising radiation as a combined preparation for separate or sequential use in tumour therapy.
Dependencies are inferred from the claim text.