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US 2007/0185082 A1Published application
Treating rhinitis by topically administering an epinastine solution to the nasal mucous membrane
OwnerVolker TRACH, Gerold Duschlerinventors
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Abstract
A method for treating allergic rhinitis, comprising topically administering to the nasal mucus membrane of a host in need of such treatment a solution comprising: epinastine, optionally in the form of its racemate, its enantiomers, or its pharmacologically acceptable acid addition salts, in a pharmacologically acceptable carrier.
Claims28
1-55. (canceled)
A method for treating allergic rhinitis comprising:
- topically administering to the nasal mucous membrane of a host in need thereof, a solution comprising epinastine, optionally in the form of its racemate, an enantiomer thereof, or a pharmacologically acceptable acid addition salt thereof, in a pharmacologically acceptable carrier.
A method for treating allergic rhinitis by topically administering to the nasal mucous membrane of a host in need of such treatment a solution comprising:
- (a) epinastine, optionally in the form of its racemate, an enantiomer thereof, or a pharmacologically acceptable acid addition salt thereof, in a concentration of 0.005 to 0.5 mg/ml of solution;
- (b) water or physiologically acceptable saline;
- and
- (c) a preservative,
- wherein the pH is adjusted to between 6.5 and 7.2 by means of a physiologically acceptable buffer, and
- optionally also including one or more chelating agents, viscosity agents, penetration promoters, antioxidants, or substances to adjust the tonicity of the solution.
3 more elements
Dependencies are inferred from the claim text.