Back to results
US 2007/0185042 A1Published application
Sirna based methods for treating alzheimer's disease
AssigneeThe Brigham and Women's Hospital, Inc. President and Fellows of Harvard College
InventorsLi-Huei Tsai, Kenneth Kosik
Life of this patent
Estimating the term…
Abstract
The present invention relates to siRNA molecules derived from BACE1 and BACE2 genes. Accordingly, provided herein are siRNA molecules comprising a nucleotide sequence consisting essentially of a BACE1 or BACE2 gene. Also provided are methods for reducing the level of BACE1 protein in a cell. Further provided are methods for preparing a pharmaceutical composition comprising an siRNA with a pharmaceutically acceptable carrier.
Claims20
An siRNA molecule comprising a nucleotide sequence consisting essentially of a sequence set forth in SEQ ID NO:
- 1.
Dependencies are inferred from the claim text.