Novel Polypeptide Hormone Phosphatonin
AssigneeUniversity College London
InventorPeter Rowe
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Abstract
The present invention relates to a novel human protein called phosphatonin, and isolated polynucleotides encoding this protein. Also provided are vectors, host cells, antibodies, and recombinant methods for producing this human protein. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to this novel human protein.
Claims20
1-30. (canceled)
An isolated polynucleotide encoding a biologically active polypeptide having phosphatonin activity.
A vector comprising a polynucleotide encoding a biologically active polypeptide having phosphatonin activity.
A host cell having operatively inserted therein a polynucleotide encoding a biologically active polypeptide having phosphatonin activity.
A process for producing a polypeptide having phosphotonin activity, comprising:
- providing a host cell having operatively inserted therein a polynucleotide encoding a biologically active polypeptide having phosphotonin activity;
- culturing the host cell;
- and
- recovering a polypeptide encoded by the polynucleotide wherein the recovered polypeptide has phosphotonin activity.
A nucleic acid molecule comprising at least 15 nucleotides, wherein the nucleic acid molecule hybridizes specifically with a polynucleotide which encodes a biologically active polypeptide having phosphotonin activity or with a polynucleotide complementary strand thereof.
An isolated regulatory sequence of a promoter regulating the expression of a nucleotide molecule comprising a polynucleotide encoding a biologically active polypeptide having phosphotonin activity.
A recombinant DNA molecule comprising a regulatory sequence of a promoter regulating the expression of a nucleic acid molecule comprising a polynucleotide encoding a biologically active polypeptide having phosphotonin activity.
Dependencies are inferred from the claim text.