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US 2007/0185009 A1Published application
Coated catheters
AssigneeImarx Therapeutics, Inc.
InventorEvan Unger
Life of this patent
Estimating the term…
Abstract
Provided herein are coated medical devices. More specifically, at least a portion of the device (e.g., catheter) is coated with an active component, wherein the active component prevents or treats occlusions and the formation(s) thereof.
Claims24
A coated medical device that reduces the incidence of, and/or prevents occlusions from, forming on the device, and/or caused by the presence of the device, the device comprising:
- (a) a device having a body;
- (b) at least one active component selected from a group consisting of a drug, a peptide, a ligand, a protein, and an antibody;
- and
- (c) at least one bi-functional poly(alkylene glycol) disposed between the body and the active component, wherein the bi-functional poly(alkylene glycol) is bound at one end to the body and bound at the other end to the active component.
1 more element
A coated medical device that reduces the incidence of, and/or prevents occlusions from, forming on the device, and/or caused by the presence of the device, the device comprising:
- (a) a device having a body;
- (b) at least one carbon-containing component;
- (c) at least one fluorinated component disposed between the body and the carbon-containing component;
- (d) at least one active group, the active group being a plasminogen activator and/or a fibrinolytic enzyme;
- and
- (e) at least one head group containing one or more phosphate groups disposed between the active group and the carbon-containing component.
3 more elements
Dependencies are inferred from the claim text.