Clinical diagnostic reagent and diagnostic method for testing infection of adult taenia solium and taenia saginata
OwnerMinoru Nakao, Akira Itoinventors
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OwnerMinoru Nakao, Akira Itoinventors
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Present invention provides a diagnostic means for testing infection of adult in humans parasitized with adult Taenia solium and Taenia saginata. It was found that a hydrophobic ligand binding protein (HLBP) derived from an adult separated from tapeworms has an antigenicity. The present invention is a clinical diagnostic reagent for testing infection of adult Taenia solium and Taenia saginata, comprising, as a main ingredient, (a) a peptide containing at least residues 22-65 of residues 20-85 of any amino acid sequence of SEQ ID NOs: 1 to 4 or (b) a peptide containing an amino acid sequence of SEQ ID NO: 5. It is possible to examine the adult infection of Taenia solium and Taenia saginata by reacting the clinical diagnostic reagent with serum from a subject (human).
A clinical diagnostic reagent for testing infection of adult Taenia solium and Taenia saginata, comprising, as a main ingredient, (a) a peptide containing at least residues 22-65 of residues 20-85 of any amino acid sequence of SEQ ID NOs:
A diagnostic method for testing infection of adult Taenia solium and Taenia saginata, comprising the steps of (i) fixing (a) a peptide comprising at least residues 22-65 of residues 20-85 of any amino acid sequence of SEQ ID NOs:
A diagnostic kit for testing infection of adult Taenia solium and Taenia saginata in serum from a subject, comprising (a) a peptide containing at least residues 22-65 of residues 20-85 of any amino acid sequence of SEQ ID NOs:
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