Device based on nitinol , a process for its production, and its use
AssigneeCeloNova BioSciences Germany GmbH
InventorsAndreas Schussler, Michael Grunze, Roman Denk
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Abstract
The present invention relates to a device comprising a substrate based essentially on nitinol and, arranged thereon at least partially, a covering or a coating based on at least one polyphosphazene derivative having the general formula (I), a process for its production, and the use of the device as an artificial implant, vascular or nonvascular stent, catheter, thrombolectomy or embolectomy catheter, fragmentation spindle or catheter, filter, vascular connector, hernia patch, oral, dental or throat implant or urether.
Claims22
A device comprising a substrate substantially comprising nitinol and a covering arranged at least partially on the substrate, wherein the covering comprises a polymer having the general formula (I),
- wherein n is 2 to ∞, the radicals R1 to R6 are identical or different and are selected from an alkoxy, alkyl sulfonyl, dialkylamino, aryloxy radical, a heterocycloalkyl radical having nitrogen as a hetroatom, and a heteroaryl radical having nitrogen as a heteroatom, wherein the polymer is capable of withstanding degradation under processing conditions of the device.
The device as claimed in claim 21, wherein the organosilicon compound is aminopropyl-trimethoxysilane.
A process for the production of a device, comprising:
- (a) providing a substrate substantially comprising nitinol,
- (b) exposing the substrate to a plasma treatment, and
- (c) coating the substrate with at least one polymer according to formula (I),
- wherein n is 2 to ∞, the radicals R1 to R6 are identical or different and are selected from an alkoxy, alkyl sulfonyl, dialkylamino, aryloxy radical, a heterocycloalkyl radical having nitrogen as a heteroatom, and a heteroaryl radical having nitrogen as a heteroatom to form the device, wherein the polymer is capable of withstanding degradation under processing conditions of the device.
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Dependencies are inferred from the claim text.