Herbal composition for treating CD33+ acute and chronic myeloid leukemia and a method thereof
AssigneeCouncil of Scientific and Industrial Research
InventorsSantu Bandyopadhyay, Keshab Roy, Mitali Ray, Goutam Banerjee, Bikash Pal, Tanusree Biswas, Samir Bhattacharya
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Abstract
A method of treating CD33+ acute and chronic myeloid leukemia in animals including humans, using fraction nos. 1 and 9 obtained from water:methanol fraction by column chromatography, with ratio of water and methanol ranging between 1:5 to 5:1, wherein said water:methanol fraction is obtained from the polar extract of Piper betel by HPLC, with retention time of 3.6 and 24.0 minutes respectively, with said fractions used both individually, and in combination.
Claims31
A method of treating Myeloid leukemia in animals including human beings, said method comprising reducing levels of monocytes by administering a pharmaceutically effective amount of betel leaf extract, lyophilized betel leaf extract or a composition comprising betel leaf extract to an animal, including a human being that is suffering from Myeloid leukemia.
A method for the treatment of myeloid leukemia in animals including human beings by reducing levels of monocytes, comprising the step of administering a pharmaceutically effective amount of betel extract.
A method of providing anti-monocytic activity in the blood cells of an animal, by administering a pharmaceutically effective amount of betel leaf as a composition comprising betel leaf extract to provide anti-monocytic activity in blood cells.
A method of destroying monocytes present in human peripheral mononuclear cells (PBMSs) using betel leaf extract, lyophilized betel leaf extract or a composition comprising betel leaf extract, said method comprising treating PBMCs with a pharmaceutically effective amount of betel leaf extract, lyophilized betel leaf extract or a composition comprising betel leaf extract.
31-47. (canceled)
Dependencies are inferred from the claim text.