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US 2007/0184110 A1Published application
Dipyridamole extended-release formulations and process for preparing same
OwnerMinutza Leibovici, Itamar Kanari +1inventors
InventorsMinutza Leibovici, Itamar Kanari, Michael Fox
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Abstract
The invention is directed to a dipyridamole formulation comprising an extended release formulation of dipyridamole and a pharmaceutically acceptable carboxylic acid, wherein the formulation is in a tablet solid form having a diameter of about 1.5 mm to about 3 mm. Optionally, the formulation may further comprise an immediate release acetylsalicylic acid formulation.
Claims31
A dipyridamole formulation comprising:
- an extended release formulation of dipyridamole and a pharmaceutically acceptable carboxylic acid, wherein the formulation is in a mini-tablet solid form having a diameter of about 1.5 mm to about 3 mm.
A process for making a dipyridamole formulation comprising:
- mixing dipyridamole and at least one carboxylic acid;
- shaping the mixture into a mini-tablet;
- coating the mini-tablet with an extended release coating;
- forming an immediate release formulation of acetylsalicylic acid;
- and
- combining the coated mini-tablet and the immediate release formulation.
3 more elements
Dependencies are inferred from the claim text.