Blister packaging for acute pain regimens
AssigneeAPR Applied Pharma Research S.A.
InventorsNorman Schellenger, William Maichle, Carl Whatley, Giorgio Reiner, Alberto Reiner
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Abstract
Provided are rapidly bioavailable solid oral dosage forms of acute pain medications, and moisture resistant packaging that enables the formulation of such rapidly bioavailable tablet dosage forms. Also provided is packaging that discourages the use of rapidly bioavailable acute pain medications for off-label chronic pain treatment, and that allows such dosage forms to be manufactured and stored for prolonged periods of time.
Claims20
1) A method of packaging a rapidly bioavailable diclofenac dosage form to discourage its use in the treatment of chronic pain comprising:
- a) formulating diclofenac in a rapidly bioavailable tablet dosage form comprising an excipient base;
- and
- b) packaging said drug in a blister package divided into from five to fourteen medication segments, wherein:
- i) each medication segment corresponds to one day of treatment, and
- ii) each medication segment is divided into from one to four unit doses corresponding to a daily dosage for said drug.
19) A method of treating acute pain comprising:
- a) providing diclofenac in a dosage form that is characterized by:
- i) an excipient base that provides rapid bioavailability;
- and
- ii) blister packaging divided into from five to fourteen medication segments, wherein each medication segment corresponds to one day of treatment, and each medication segment is divided into from one to four unit doses corresponding to a daily dosage for said drug;
- and
- b) administering said diclofenac to a patient suffering from acute pain.
20) A method of packaging an acute pain medication to discourage its use in the treatment of chronic pain comprising:
- a) formulating said drug in a rapidly bioavailable dosage form;
- and
- b) packaging said drug in a blister package divided into from five to fourteen medication segments, wherein:
- i) each medication segment corresponds to one day of treatment, and
- ii) each medication segment is divided into from one to four unit doses corresponding to a daily dosage for said drug.
Dependencies are inferred from the claim text.