39-desmethoxyrapamycin, compositions and methods of use thereof

A method of treating a condition in a patient, in need thereof, comprising the administration of an effective amount of a medicament comprising 39-desmethoxyrapamycin or pharmaceutically acceptable salt thereof, wherein said condition is selected from the group consisting of transplantation rejection, graft vs. host disease, autoimmune disorders, diseases of inflammation, vascular disease, restenosis, fibrotic diseases, and fungal infections.

A kit comprising (i) 39-desmethoxyrapamycin, or a pharmaceutically acceptable salt thereof and (ii) at least one other therapeutically effective agent.

A method for the induction or maintenance of immunosuppression in a patient, in need thereof, comprising the administration of an effective amount of a medicament comprising 39-desmethoxyrapamycin or pharmaceutically acceptable salt thereof.

A method for the stimulation of neuronal regeneration in a patient, in need thereof, comprising the administration of an effective amount of a medicament comprising 39-desmethoxyrapamycin or pharmaceutically acceptable salt thereof.