Cyclopropyl Fused Indolobenzazepine HCV NS5B Inhibitors

A compound of formula I

• wherein:
• R1 is CO2R5 or CONR6R7;
• R2 is hydroxy, alkoxy, benzyloxy, NR8R9, or
• R3 is hydrogen, halo, alkyl, alkenyl, hydroxy, benzyloxy, or alkoxy;
• R4 is C5-7cycloalkyl;
• R5 is hydrogen or alkyl;
• R6 is hydrogen, alkyl, cycloalkyl, alkoxy, or SO2R10;
• R7 is hydrogen, alkyl, or cycloalkyl;
• or NR6R7 taken together is pyrrolidinyl, piperidinyl, piperazinyl, N-(alkyl)piperazinyl, homomorpholinyl, homopiperidinyl, morpholinyl, or thiomorpholinyl;
• R8 is hydrogen, alkyl, cycloalkyl, hydroxyalkyl, alkoxyalkyl, aminoalkyl, alkylaminoalkyl, dialkylaminoalkyl, (CO2R5)alkyl, or (CON(R5)(R5))alkyl;
• R9 is hydrogen, alkyl, cycloalkyl, hydroxyalkyl, dihydroxyalkyl, alkoxyalkyl, aminoalkyl, alkylaminoalkyl, dialkylaminoalkyl, (CO2R5)alkyl, or (CON(R5)(R5))alkyl;
• or NR8R9 taken together is pyrrolidinyl, piperidinyl, piperazinyl, homomorpholinyl, homopiperidinyl, morpholinyl, or thiomorpholinyl, and is substituted with 0-2 substitutents selected from halo, hydroxy, alkyl, hydroxyalkyl, alkoxyalkyl, amino, alkylamino, dialkylamino, aminoalkyl, alkylaminoalkyl, dialkylaminoalkyl, pyrrolidinyl, piperidinyl, piperazinyl, N-(alkyl)piperazinyl, morpholinyl, thiomorpholinyl, and pyridinyl;
• and
• R10 is alkyl, haloalkyl, cycloalkyl, phenyl, amino, alkylamino, dialkylamino, benzylamino, or (benzyl)(alkyl)amino;
• or R10 is pyrrolidinyl, piperidinyl, piperazinyl, homomorpholinyl, homopiperidinyl, morpholinyl, or thiomorpholinyl, and is substituted with 0-2 substitutents selected from halo and alkyl;
• or a pharmaceutically acceptable salt thereof.