HAS2-stimulating plant extracts
AssigneesBASF Beauty Care Solutions France S.A.S., Yves Saint Laurent Parfums
InventorsEric Perrier, Anne Guezennec, Corinne Reymermier, Joelle Guesnet
Life of this patent
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Abstract
The invention relates to plant extracts for stimulating the synthesis of hyaluronan synthase, particularly the synthesis of hyaluronan synthase 2 (HAS2). Specific aims of the invention are to increase firmness and/or elasticity and/or tissue moisturization, and/or increase the skin barrier effect, and/or increase tissue resilience, and/or modulate angiogenesis, or the neocreation of blood capillaries, and/or improve healing, and/or cell proliferation, migration or differentiation, and/or skin atrophy, and/or intended to combat the effects of ageing on the skin, and in particular to combat the loss of firmness of the skin observed in the course of ageing, and/or atrophied scars.
Claims9
A method of stimulating the expression and/or the activity of hyaluronan synthase 2 (HAS2) in fibroblast cells of cutaneous tissue, said method comprising the step of topically applying to cutaneous tissue a composition comprising
- (a) an effective amount of at least one stimulating agent selected from the group consisting of Guarana (Paullinia cupana), St. John's wort (Hypericum hircinum), bamboo (Bambusa vulgaris), mung bean (Phaseolus aureus), gooseberry (Ribes uva-crispaz), butcher's broom (Ruscus aculeatus), broad bean (Vicia faba equina), pea (Pisum sativum), lupin (lupinus angustifolius), Ephedra (Ephedra sinica), tansy (Tanacetum vulgare), Indian shell flower (Alpinia galanga), white mulberry (Morus alba), J'oublie (Pentadiplandra brazzeana), and mixtures thereof;
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- (b) a dermatologially acceptable carrier.
A topical cosmetic composition comprising
- (a) an effective amount of at least one plant extract capable of stimulating the expression or the activity of hyaluronan synthase, wherein said plant extract is an extract of a plant selected from the group consisting of Guarana (Paullinia cupana), St. John's wort (Hypericum hircinum), bamboo (Bambusa vulgaris), mung bean (Phaseolus aureus), gooseberry (Ribes uva-crispa), butcher's broom (Ruscus aculeatus), broad bean (Vicia faba equina), pea (Pisum sativum), lupin (lupinus angustifolius), Ephedra (Ephedra sinica), tansy (Tanacetum vulgare), Indian shell flower (Alpinia galanga), white mulberry (Morus alba), J'oublie (Pentadiplandra brazzeana), and mixtures thereof;
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- (b) at least one cosmetically acceptable excipient.
Dependencies are inferred from the claim text.