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AssigneeMitsubishi Rayon Co., Ltd.
InventorsIsao Tanaka, Nobuhisa Watanabe, Hiroshi Takeuchi, Takayuki Iseki, Nozomu Shibuya, Chiharu Nishijima
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The invention provides a protein crystallizing device capable of performing a protein crystallization experiment or screening of crystallization conditions rapidly and economically with a high reliability, and a protein crystallizing agent capable of performing the operation of protein crystallization by a simpler method. The protein crystallizing device of the present invention comprises a protein crystallizing microarray having at least two crystallizing agent holding parts which hold a protein crystallizing agent and a plate laminated on the protein crystallizing microarray, wherein the plate has crystallizing sections corresponding to the crystallizing agent holding parts and capable of being filled with a protein-containing sample and recessed parts provided between the crystallizing sections. The protein crystallizing agent of the present invention is evenly held in a gel by gelatinizing a solution containing a protein precipitant and an unsaturated monomer.
A protein crystallizing device comprising:
A protein crystallizing gel comprising sodium chloride held in a gel-like material comprising a monomer selected from a group consisting of acrylamide, 2-acrylamide-2-methylpropanesulfonic acid, and methacryldimethylaminoethylmethyl chloride salt.
A protein crystallizing gel comprising 2-methyl-2,4-pentanediol held in a gel-like material comprising dimethylacrylamide.
A protein crystallizing agent comprising sodium/potassium phosphate held in a gel-like material comprising 2-acrylamide-2-methylpropanesulfonic acid.
A protein crystallizing gel comprising ammonium sulfate held in a gel-like material comprising methacryldimethylaminoethylmethyl chloride salt.
A protein crystallizing gel comprising sodium malonate held in a gel-like material comprising acrylamide.
A protein crystallizing gel comprising polyethylene glycol 6000 held in a gel-like material comprising polyoxyethylene monoacrylate.
Dependencies are inferred from the claim text.