Adjusting ph in a method of separating whole blood
AssigneeGambro Bct, Inc.
InventorsThomas FELT, Bruce GIBBS, Peter PIHLSTEDT
Life of this patent
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Abstract
This invention is directed to a method of collecting and separating whole blood into components. The method includes the steps of adding an anticoagulant having an acidic pH to a bag for collecting and/or separating whole blood, collecting whole blood in the bag, loading the bag containing anticoagulated whole blood on a rotor, spinning the bag on the rotor to separate the whole blood into at least one component; and squeezing the bag on the rotor to push the component from the separation bag into at least one satellite bag.
Claims23
A method of collecting and separating whole blood into at least one component comprising the steps of:
- adding an anticoagulant having an acidic pH to a bag for collecting and/or separating whole blood;
- collecting whole blood in the bag;
- loading the bag containing anticoagulated whole blood on a rotor;
- spinning the bag on the rotor to separate the whole blood into at least one component;
- and
- squeezing the bag on the rotor to transfer the at least one component from the separation bag into a satellite bag.
A method of separating red blood cells from previously collected and stored whole blood comprising the steps of:
- collecting whole blood in CPD anticoagulant;
- storing the anticoagulated whole blood overnight;
- loading the anticoagulated whole blood on a rotor;
- spinning the rotor to separate the whole blood into at least a red blood cell component;
- squeezing the blood on the rotor to transfer at least the red blood cell component into a satellite bag;
- and
- increasing the pH of the separated red blood cell component in the satellite bag.
A method for separating whole blood into components comprising the steps of:
- collecting whole blood into a bag containing an anticoagulant having an acidic pH;
- loading the bag containing the anticoagulant and whole blood onto a rotor;
- spinning the rotor to separate the whole blood into a plasma component, a platelet component and a red blood cell component;
- squeezing the bag on the rotor to transfer the plasma component into a first satellite bag;
- squeezing the bag on the rotor to transfer the platelet component into a second satellite bag;
- and
- squeezing the bag on the rotor to transfer the red blood cell component into a third satellite bag.
A pre-connected bag and solution set comprising:
- a collection bag containing anticoagulant solution having an acidic pH;
- a separation bag pre-connected via transfer tubing to the collection bag;
- and
- at least one satellite bag pre-connected via transfer tubing to the separation bag.
A pre-connected bag and solution set comprising:
- a separating bag containing anticoagulant solution having an acidic pH;
- and
- at least one satellite bag pre-connected via tubing to the separating bag.
Dependencies are inferred from the claim text.