Method and Apparatus for Noninvasively Estimating a Property of an Animal Body Analyte from Spectral Data
OwnerTimothy Ruchti, Thomas Blank +1inventors
InventorsTimothy Ruchti, Thomas Blank, Alexander Lorenz
Life of this patent
Estimating the term…
Abstract
A method and apparatus for calibration development using clustering is disclosed. More particularly, the invention relates to subsequent calibration development using clusters that are individually interference compensated and to subsequent estimation. Estimation of analyte property values from data, such as noninvasive spectra, is improved by a calibration method that uses clusters that are individually interference-compensated.
Claims38
A method for generating a model for noninvasive estimation of an analyte property of blood or tissue from spectral data, comprising the steps of:
- clustering the spectral data into a plurality of clusters;
- removing interference from each of said clusters to yield respective interference-reduced clusters;
- aggregating said interference-reduced clusters into a calibration data set;
- and
- generating said model from said calibration data set.
An apparatus for noninvasive analyte property estimation of a human subject having skin and a sample site, comprising:
- a source of light energy;
- a detector of light energy for acquiring spectral data;
- a sample interface, the source and detector being disposed therein;
- and
- an estimation component for estimating the analyte property from the spectral data, the estimation component comprising a calibration model component having an architecture of at least two clustered spectral data sets and means for removing separate cluster related interference from each of said clustered spectral data sets.
An apparatus for noninvasive analyte property estimation of a subject having skin and a sample site, comprising:
- a source of light energy;
- a detector of light energy for acquiring spectral data;
- a sample interface, the source and detector being disposed therein;
- and
- an estimation component comprising a processor and memory, the memory being coupled to the processor and comprising a plurality of processor instructions for:
- controlling the acquisition of the spectral data;
- clustering the spectral data into a plurality of clusters;
- removing interference from each of the clusters to yield respective interference-reduced clusters;
- aggregating the interference-reduced clusters into a calibration data set;
- and
- generating a model for the analyte property estimation from the calibration data set.
Dependencies are inferred from the claim text.