Apparatus and Method for Monitoring Tissue Vitality Parameters
AssigneeCritiSense, Ltd.
InventorsEliahu Pewzner, Avraham Mayevsky
Life of this patent
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Abstract
Apparatus for determining the oxygenation state of at least one tissue element, comprising: a) illumination means for illuminating said tissue element with an illuminating radiation at a predetermined wavelength via at least one illumination location with respect to said tissue element, said illuminating radiation being at a wavelength within the NADH excitation spectrum or the Fp excitation spectrum; b) radiation receiving means and detection means for measuring the intensity of the corresponding NADH fluorescence or Fp fluorescence emitted by the tissue element at at least two predetermined wavelengths within the range of wavelengths comprised within the corresponding fluorescence emission spectrum.
Claims21
Apparatus for determining the oxygenation state of at least one tissue element, comprising:
- a) illumination means for illuminating said tissue element with an illuminating radiation at a predetermined wavelength via at least one illumination location with respect to said tissue element, said illuminating radiation being at a wavelength within the NADH excitation spectrum or the Fp excitation spectrum;
- b) radiation receiving means and detection means for measuring the intensity of the corresponding NADH fluorescence or Fp fluorescence emitted by the tissue element at at least two predetermined wavelengths within the range of wavelengths comprised within the corresponding fluorescence emission spectrum.
Method for determining the oxygenation state of a tissue element, comprising:
- (a) providing an illuminating radiation to the tissue element, said illuminating radiation being at a wavelength within one of the NADH fluorescence excitation spectrum or the Fp fluorescence excitation spectrum;
- (b) measuring the intensity of the corresponding NADH fluorescence or Fp fluorescence, respectively, emitted by the tissue element at least at two predetermined wavelengths within the range of wavelengths comprised in the corresponding fluorescence emission;
- (c) comparing the intensities measured in (b) to provide an estimate of the relative levels of oxygenated blood to deoxygenated blood in said tissue element.
Dependencies are inferred from the claim text.