Method of treating pediatric patients with corticosteroids
OwnerR. Plottinventor
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Abstract
The present invention comprises a method of treating pediatric patients suffering from an inflammatory or pruritic skin disorder comprising topically applying fluocinonide to an affected area. Treatment according to this method does not result in clinically significant suppression of the HPA-axis.
Claims18
A method of treating pediatric patients suffering from a corticosteroid-responsive inflammatory or pruritic skin disorder comprising topically applying fluocinonide to an affected area wherein said application does not result in clinically significant HPA-axis suppression.
A method of treating pediatric patients suffering from a corticosteroid-responsive inflammatory or pruritic skin disorder comprising topically applying a composition comprising a corticosteroid;
- two or more penetration enhancers selected from the group consisting of diisopropyl adipate, dimethyl isosorbide, propylene glycol, 1,2,6-hexapetriol, and benzyl alcohol;
- and one or more of the group consisting of solvents and emulsifiers, wherein the penetration enhancers are present in a ratio to a total of the penetration enhancers, and solvents and emulsifiers of at least about 0.90, to an affected area wherein said application does not result in clinically significant HPA-axis suppression.
A method of treating pediatric patients suffering from a corticosteroid-responsive inflammatory or pruritic skin disorder comprising topically applying a composition comprising 71.08% propylene glycol USP, 15.00% dimethyl isosorbide, 7.50% glyceryl monostearate and PEG stearate, 2.50% glyceryl monostearate NF, 2.49% purified water, 1.20% carbopol 980, 0.12% diisopropanolamine 85%, 0.10% fluocinonide (micronized) USP, and 0.01% citric acid USP, to an affected area wherein said application does not result in clinically significant HPA-axis suppression.
Dependencies are inferred from the claim text.