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US 2007/0178599 A1Published application
Methods for drug discovery, disease treatment, and diagnosis using metabolomics
AssigneesMetabolon, Inc., Cornell Research Foundation, Inc.
InventorsRima Kaddurah-Daouk, Bruce Kristal
Life of this patent
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Abstract
The small molecule profiles of cells are compared to identify small molecules which are modulated in altered states. Cellular small molecule libraries, methods of identifying tissue sources, methods for treating genetic and non-genetic diseases, and methods for predicting the efficacy of drugs are also discussed.
Claims18
A method for metabolomically identifying small molecules indicative of an oncological disorder, comprising:
- obtaining a small molecule profile from a subject suffering from said oncological disorder;
- and
- comparing the small molecule profile from the subject to a standard small molecule profile, thereby identifying small molecules indicative of said oncological disorder.
A method for metabolomically predicting whether a subject is predisposed to having an oncological disorder, comprising:
- obtaining a small molecule profile from the subject;
- and
- comparing the small molecule profile from the subject to a standard small molecule profile, thereby predicting whether a subject is predisposed to having an oncological disorder.
Dependencies are inferred from the claim text.