Circuits and methods for artifact elimination

A method for acquiring electrical signals from a physical system comprising:

• providing an excitation to the physical system by way of a physical interface to the system or detecting the presence of an excitation in the physical system;
• and
• actively eliminating interference that arises from the excitation using signal acquisition coupled to the physical interface.

Apparatus comprising:

• stimulation circuitry that electrically stimulates a biological specimen by way of a physical interface to the biological specimen or detects the presence of a confounding signal in the biological specimen;
• and
• signal acquisition circuitry that actively manipulates the physical interface or the biological specimen to eliminate interference arising from the stimulation or confounding signal.

A method for acquiring electrical signals from a biological specimen comprising:

• providing electrical stimulus to the specimen or detecting the presence of a confounding signal in the specimen;
• and
• actively eliminating interference that arises from the stimulation or confounding signal using signal acquisition.