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US 2007/0178576 A1Published application
Purification of high-molecular compounds by means of affinity membrane chromatography
AssigneesSartorius AG, Apanovis Biotechnologie GmbH
InventorsWolfgang Demmer, Matthias Grabosch, Oscar-Werner Reif, Wolfgan Nagel, Mariel Donzeau, Peter Reichelt
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Abstract
The invention relates to a method for purifying and/or isolating high-molecular compounds, such as high-molecular proteins or protein-type compounds, contained in a solution or a suspension, by means of affinity chromatography using membranes containing metal ions.
Claims16
Method for purifying and/or isolating high-molecular compounds contained in a solution or a suspension with the capacity for metal chelate formation, comprising the steps:
- (a) Application of the solution or suspension onto a metal ions containing membrane, and
- (b) affinity chromatographic separation of the high-molecular compounds by binding them to the metal ion containing membrane.
Dependencies are inferred from the claim text.