3714, 16742, 23546, and 13887 novel protein kinase molecules and uses therefor
AssigneeMillennium Pharmaceuticals, Inc.
InventorsRachel Meyers, John Hunter
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AssigneeMillennium Pharmaceuticals, Inc.
InventorsRachel Meyers, John Hunter
Estimating the term…
The invention provides isolated nucleic acids molecules, designated 3714, 16742, 23546, or 13887 nucleic acid molecules, which encode novel protein kinases. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 3714, 16742, 23546, or 13887 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 3714, 16742, 23546, or 13887 gene has been introduced or disrupted. The invention still further provides isolated 3714, 16742, 23546, or 13887 proteins, fusion proteins, antigenic peptides and anti-3714, -16742, -23546, or -13887 antibodies. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided.
An isolated 3714, 16742, 23546, or 13887 nucleic acid molecule selected from the group consisting of:
An isolated 3714, 16742, 23546, or 13887 polypeptide selected from the group consisting of:
A method for identifying a compound capable of treating cancer or a cellular proliferation and/or differentiation disorder characterized by aberrant 3714, 16742, 23546, or 13887 nucleic acid expression or 3714, 16742, 23546, or 13887 polypeptide activity comprising assaying the ability of the compound to modulate 3714, 16742, 23546, or 13887 nucleic acid expression or 3714, 16742, 23546, or 13887 polypeptide activity, thereby identifying a compound capable of treating cancer or a cellular proliferation and/or differentiation disorder characterized by aberrant 3714, 16742, 23546, or 13887 nucleic acid expression or 3714, 16742, 23546, or 13887 polypeptide activity.
A method for evaluating the efficacy of a treatment of cancer or a cellular proliferation and/or differentiation disorder, in a subject, comprising:
Dependencies are inferred from the claim text.