Methods of determining relative genetic likelihoods of an individual matching a population
OwnerLucas MARTIN, Eduardas Valaitisinventors
Life of this patent
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Abstract
Provided are methods of determining an individual's relative likelihood of having a genetic match with one or more local populations as compared to a generic index population. Also provided are systems, apparatuses, kits, and machine-readable medium relating to such methods. The methods may be used for example, to identify an individual's or individual's ancestor's most likely geographic origin, or to identify the breed, species, kingdom, etc. of an organism.
Claims32
A method of determining an individual's relative likelihood of a genetic match with one or more local populations as compared to a generic index population comprising:
- determining a genetic likelihood of the individual belonging to at least one local population;
- determining a genetic likelihood of the individual belonging to a generic index population;
- and
- comparing the likelihood of the individual belonging to the at least one local population to the likelihood of the individual belonging to the generic index population to determine the individual's relative likelihood of a genetic match with the one or more local populations.
An apparatus comprising a server comprising software capable of
- determining a first likelihood of an individual belonging to a local population by comparing genetic markers present in the individual to a frequency of such genetic markers occurring in the local population;
- determining a second likelihood of the individual belonging to a generic index population by comparing the genetic markers present in the individual to a frequency of such genetic markers occurring in the generic index population;
- and
- comparing the first likelihood to the second likelihood.
A system comprising
- a server coupled to a database;
- wherein said database includes information regarding genetic markers occurring in at least one local population and information regarding genetic markers occurring in a generic index population;
- and
- wherein the server comprises software capable of
- determining a first likelihood of an individual belonging to a local population by comparing genetic markers present in the individual to a frequency of such genetic markers occurring in the local population;
- and
- determining a second likelihood of the individual belonging to a generic index population by comparing the genetic markers present in the individual to a frequency of such genetic markers occurring in the generic index population.
A kit comprising:
- at least one device for determining genetic markers of an individual;
- and
- a machine readable medium comprising
- a medium and
- a program capable of comparing genetic markers of the individual to at least one local population and comparing the genetic markers of the individual to a generic index population, to determine a relative genetic likelihood of the individual belonging to the at least one local population as compared to the generic index population.
Dependencies are inferred from the claim text.