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US 2007/0178486 A1Published application
Compositions and Methods for the Diagnosis and Treatment of Tumor
AssigneeGenentech, Inc.
InventorsAvi Ashkenazi, Dan Eaton, Audrey Goddard, Austin Gurney, William Wood, Thomas Wu
Life of this patent
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Abstract
The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
Claims21
1-14. (canceled)
An isolated antibody which binds to:
- (a) the polypeptide shown in FIG. 2 (SEQ ID NO:2);
- (b) the polypeptide shown in FIG. 2 (SEQ ID NO:2), lacking its associated signal peptide;
- (c) a polypeptide encoded by the nucleotide sequence shown in FIG. 1 (SEQ ID NO:1);
- (d) a polypeptide encoded by the full-length coding sequence of the nucleotide sequence shown in FIG. 1 (SEQ ID NO:1);
- or
- (e) a polypeptide encoded by the full-length coding sequence of the cDNA deposited under ATCC accession number 203127.
3 more elements
An isolated polypeptide comprising an amino acid sequence having at least 90% amino acid sequence identity to:
- (a) the amino acid sequence shown in FIG. 2 (SEQ ID NO:2);
- (b) the amino acid sequence shown in FIG. 2 (SEQ ID NO:2), lacking its associated signal peptide;
- (c) an amino acid sequence encoded by the nucleotide sequence shown in FIG. 1 (SEQ ID NO:1);
- (d) an amino acid sequence encoded by the full-length coding sequence of the nucleotide sequence shown in FIG. 1 (SEQ ID NO:1);
- or
- (e) an amino acid sequence encoded by the full-length coding sequence of the cDNA deposited under ATCC accession number 203127.
3 more elements
Dependencies are inferred from the claim text.