Storage-stable cellular whole blood composition containing elevated amounts of D-dimer
AssigneeBio-Rad Laboratories, Inc.
InventorsTimothy Ho, Sholeh Zaminasli, James Cole, Alireza Ebrahim
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Abstract
The present invention provides a cellular whole-blood D-dimer composition for use with diagnostic test procedures for D-dimer, and a method of its preparation. The composition comprises human erythrocytes and processed plasma to which D-dimer, and stabilizers, and optionally antimicrobial agents, are added and can be used as a standard and control for D-dimer testing.
Claims48
A whole blood cellular composition that comprises a defibrinated plasma having a pH of from about 4 to about 9, a total protein content of from 0 to about 10 g/dL, erythrocytes, one or more stabilizers and an elevated level of D-dimer.
A composition according to claim 15 wherein the protease inhibitor comprises a serine protease inhibitor.
Dependencies are inferred from the claim text.