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US 2007/0178157 A1Published application
Process for cleaning hard gelatine capsules
AssigneeBoehringer Ingelheim Pharma GmbH & Co. KG
InventorsHerbert Wachtel, Petra Schmidt-Joerg, Volker Freudenberger
Life of this patent
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Abstract
A process which can be used in the laboratory or on an industrial scale for cleaning the inner wall of hard gelatine capsules, in which the sealed capsules are cleaned with a powder formulation.
Claims17
1-14. (canceled)
A process for cleaning the inner wall of a hard gelatine capsule for use in inhalation therapy, wherein the process comprises:
- (a) subjecting the powder formulation to one or more screenings and mixings;
- (b) transferring the powder formulation obtained from step (b) into a gelatine capsule for inhalation;
- (c) agitating the gelatine capsules from step (b) in a mixing container;
- (d) visually monitoring the cleaning process to a selected endpoint;
- and
- (e) placing the gelatine capsule directly in the inhaler or optionally emptying and refilling the gelatine capsule with the active substance formulation.
3 more elements
(canceled)
The process according to claim 195 wherein the active substance formulation contains a tiotropium powder.
Dependencies are inferred from the claim text.