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US 2007/0178153 A1Published application
Calcium Carbonate Granulation
AssigneeDelavau LLC
InventorsRaya Levin, Kevin Lang, Gregory Murphy, James Dibble
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Abstract
Highly compactable granulations and methods for preparing highly compactable granulations are disclosed. More particularly, highly compactable calcium carbonate granulations are disclosed. The granulations comprise powdered materials such as calcium carbonate that have small median particle sizes. The disclosed granulations are useful in pharmaceutical and nutraceutical tableting and provide smaller tablet sizes upon compression than previously available.
Claims20
A method for preparing a high density granulation comprising the steps of:
- (a) mixing a composition comprising a powdered material having a median particle diameter of about 0.1 to about 20 μm with water in a high shear mixer;
- and (b) drying the composition in a fluidized bed oven;
- thereby providing a granulation having a tap density between about 0.9 and about 2.0 g/cm3.
Dependencies are inferred from the claim text.