Method for Treating Immune Dysfunction by Regulation of CD40 Ligand Expression
OwnerChristopher Roman, Chongmin Huaninventors
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Abstract
Techniques for treating immune dysfunction in a patient by regulation of CD40 Ligand (CD40L) expression are provided. For example, one technique includes suppressing TFE3 and/or TFEB in the patient to thereby suppress CD40L expression in the patient. In addition, the technique may include administering a TFE3 inhibitor and/or a TFEB inhibitor for suppressing TFE3 and/or TFEB, respectively, in the patient.
Claims20
A method of treating at least one of an immunological disease and an inflammatory disease in a patient, the method comprising the step of suppressing at least one of TFE3 and TFEB in the patient to thereby suppress CD40L expression in the patient.
Dependencies are inferred from the claim text.