Treatment of presbyopia with picolinic acid and its analogs
OwnerNathan Ravi, Paul Hamiltoninventors
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Abstract
Compositions and methods for inhibiting the growth of lens epithelial cells are provided. The compositions provided include a chelating agent in an amount sufficient for inhibiting the growth of lens epithelial cells. The compositions and methods provided may also be used for the treatment of disorders of the eye, especially in the treatment of presbyopia.
Claims39
A composition for inhibiting the growth of lens epithelial cells, comprising:
- a chelating agent in an amount sufficient to inhibit lens epithelial cell growth;
- and
- a carrier.
A pharmaceutical composition for topical application to the eye, comprising:
- a chelating agent in an amount sufficient to inhibit lens epithelial cell growth;
- and
- one or more excipients.
A pharmaceutical composition for the treatment or prevention of presbyopia, comprising:
- a chelating agent in an amount sufficient to inhibit lens epithelial cell growth;
- and
- one or more excipients.
A method for inhibiting the growth of lens epithelial cells, comprising:
- providing lens epithelial cells;
- and
- contacting the lens epithelial cells with a composition comprising a chelating agent in an amount sufficient to inhibit lens epithelial cell growth.
A method for treating or preventing a disorder of an eye, comprising:
- topically applying to the eye a composition comprising:
- a chelating agent in an amount sufficient to inhibit lens epithelial cell growth;
- and
- one or more excipients.
Dependencies are inferred from the claim text.