US 2007/0175809 A1 · Reusable Liquid Chromatographic Columns

Abstract

A reusable liquid chromatographic column consists of three parts, a column body with an integral outlet port molded on one end, a sealing insert with an inlet port, and a perforated cap providing downward force to compress the sealing insert into the column body. A wedge-like seal is employed to seal the connection between the sealing insert and the column body. Two filters on both ends of the column body are used to prevent escape of packing materials from the column chamber under pressure. Hand tightening is adequate to seal the connection by screwing the perforated cap onto the column body. The column is reusable due to its simple disassembling and reassembling processes. It is also disposable due to its inexpensive fabricating materials and manufacturing process.

Claims22

Dependent claims

A chromatographic column comprising:

a tubular column body having an inlet end with an opening for loading the packing materials and sealing and the other end with an outlet port molded as a single piece onto said column body for the mobile phase flowing out, said column body having a chamber to fill with the packing material from said inlet end, said column body having male threads on the outer wall of said inlet end;
a sealing insert with a molded inlet port and a side sealing slope allowing said sealing insert to slide into said inlet end of said column body to form a wedge-like seal;
a perforated cap with ridges on said outer surface and female threads on said inner surface;
two filters with one filter placed in said outlet end of said column body and another filter placed on said inlet end of said column body.

1 more element

Dependencies are inferred from the claim text.

Reusable Liquid Chromatographic Columns

Life of this patent

Reusable Liquid Chromatographic Columns

Life of this patent

Abstract

Claims22