Multi-capillary array electrophoresis device

A device comprising:

• a multi-capillary array including a plurality of capillaries filled with a separation medium, each capillary of the plurality having a respective first portion into which a sample can be introduced, and a respective light-irradiatable portion, wherein the plurality of light-irradiatable portions are arranged in a row on a plane and a substance is disposed between two or more adjacent light-irradiatable portions, the substance having a refractive index that is higher than the refractive index of air and lower than the refractive index of water;
• an excitation light source capable of emitting excitation light to simultaneously irradiate the plurality of light-irradiatable portions;
• and
• a detector capable of detecting light emitted by samples disposed within the light-irradiatable portions upon irradiation with excitation light, wherein the light-irradiatable portions are disposed in a sealed vessel that retains the liquid substance and a bubble.

A device comprising:

• a multi-capillary array including a plurality of capillaries that are filled with a separation medium, each capillary of the plurality having a respective first portion into which a sample can be introduced, and a respective light-irradiatable portion that is capable of being irradiated with excitation light, wherein the light-irradiatable portions are arranged in a row on a plane;
• a power supply capable of applying a voltage to a current path that includes the first portions and the light-irradiatable portions;
• an excitation light source capable of emitting excitation light in a direction toward the plurality of light-irradiatable portions to simultaneously irradiate the light-irradiatable portions;
• a detector capable of detecting light emitted by samples in the light-irradiatable portions upon irradiation of the samples with excitation light;
• and
• a vessel that holds a liquid fluorine-containing compound having a refractive index that is higher than the refractive index of air and lower than the refractive index of water and a bubble, in areas between two or more adjacent light-irradiatable portions, the liquid being located in a space which is interposed among the plurality of capillaries and through which the excitation light passes;
• wherein a temperature gradient of the liquid, with respect to a direction that is perpendicular to both an axial direction of the light-irradiatable portions and the direction of travel of the excitation light from the excitation light source, is substantially zero.

A device comprising:

• a multi-capillary array including a plurality of capillaries that are filled with a separation medium, each capillary of the plurality having a respective first portion into which a sample can be introduced, and a respective light-irradiatable portion that is capable of being irradiated with excitation light, wherein the light-irradiatable portions are arranged in a row on a plane;
• a power supply capable of supplying a voltage to a current path that includes the first portions and the light-irradiatable portions;
• an excitation light source capable of emitting excitation light in a direction toward the plurality of light-irradiatable portions simultaneously;
• a detector capable of detecting light emitted by samples in the light-irradiatable portions upon irradiation with excitation light;
• and
• a sealed vessel that retains a liquid fluorine-containing compound and a bubble in areas between two or more adjacent light-irradiatable portions, wherein the multi-capillary array includes a bubble-accommodating space that is capable of accommodating the gas, and the bubble-accommodating space is provided in a position through which excitation light, emitted from the excitation light source, does not pass.

A device comprising:

• a multi-capillary array including a plurality of capillaries that are filled with a separation medium, each capillary of the plurality having a respective first portion into which a sample can be introduced, and a respective light-irradiatable portion that is capable of being irradiated with excitation light, the plurality of capillaries being arranged in a row on a plane;
• an excitation light source capable of providing excitation beam paths that pass through the light-irradiatable portions of the plurality of capillaries;
• a detector for detecting emission beams emitted by samples in the light-irradiatable portions upon irradiation of the sample with excitation light;
• and
• a light-transmitting medium disposed between two or more adjacent light-irradiatable portions and being transmissive of excitation light generated by the excitation light source;
• wherein the light-transmitting medium has a shape including a curved surface disposed along an emission beam path between the light-irradiatable portions and the detector.

A device comprising:

• a multi-capillary array including a plurality of capillaries that are filled with a separation medium, each capillary of the plurality having a respective first portion into which a sample can be introduced, and a respective light-irradiatable portion that is capable of being irradiated with excitation light;
• a detector for detecting emission beams emitted by samples in the light-irradiatable portions upon irradiation with excitation light;
• and
• a vessel that holds a liquid having a refractive index that is higher than the refractive index of air, and through which passes the light-irradiatable portions;
• wherein the vessel includes a curved surface disposed along an emission beam path between the light-irradiatable portions and the detector.