Stable metal/conductive polymer composite colloids and methods for making and using the same
AssigneePharma Diagnostics N.V.
InventorsPatrick Englebienne, Anne Van Hoonacker
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Abstract
Stable metal/conductive polymer composite colloids and methods for making the same are provided. The subject colloids find use in a variety of different applications, including analyte detection applications. Also provided are kits that include the subject colloids.
Claims33
A method of producing a metal/conductive polymer composite colloid, said method comprising:
- combining:
- (i) a metal colloid;
- and
- (ii) a water-soluble conductive polymer;
- under conditions sufficient for said water-soluble conductive polymer to adsorb to metal particles of said colloid to produce a metal/conductive polymer composite colloid.
-17. (canceled)
A stable metal/conductive polymer composite colloid comprising metal particles surface coated with a conductive polymer layer and suspended in an aqueous medium.
-54. (canceled)
A stable metal/conductive polymer composite colloid comprising metal particles surface coated with a conductive polymer layer and suspended in an aqueous medium, where said particles display a ligand.
-74. (canceled)
A method for screening a sample for the presence of an analyte, said method comprising:
- (a) contacting said sample with a stable metal/conductive polymer composite colloid to produce an assay mixture, wherein said colloid metal particles surface coated with a conductive polymer layer and displaying a ligand for said analyte;
- and
- (b) detecting an optical parameter of said assay mixture to screen said sample for the presence of said analyte.
-82. (canceled)
Dependencies are inferred from the claim text.