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US 2007/0169221 A1Published application
Novel Bt toxin receptors from lepidopteran insects and methods of use
AssigneePioneer Hi-Bred International, Inc.
InventorsJohn Mathis, Terry Meyer
Life of this patent
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Abstract
The invention relates to Bt toxin resistance management. The invention particularly relates to the isolation and characterization of nucleic acid and polypeptides for a novel Bt toxin receptor. The nucleic acid and polypeptides are useful in identifying and designing novel Bt toxin receptor ligands including novel insecticidal toxins.
Claims14
An isolated nucleic acid molecule having a nucleotide sequence selected from the group consisting of:
- a) the nucleotide sequence set forth in SEQ ID NO:5;
- b) a nucleotide sequence having at least about 60% sequence identity to the nucleotide sequence set forth in SEQ ID NO:5, wherein said nucleotide sequence having at least about 60% sequence identity to the nucleotide sequence set forth in SEQ ID NO:5 has Bt toxin binding activity;
- c) a nucleotide sequence having at least about 70% sequence identity to the nucleotide sequence set forth in SEQ ID NO:5, wherein said nucleotide sequence having at least about 70% sequence identity to the nucleotide sequence set forth in SEQ ID NO:5 has Bt toxin binding activity;
- d) a nucleotide sequence having at least about 75% sequence identity to the nucleotide sequence set forth in SEQ ID NO:5, wherein said nucleotide sequence having at least about 75% sequence identity to the nucleotide sequence set forth in SEQ ID NO:5 has Bt toxin binding activity;
- e) a nucleotide sequence having at least about 85% sequence identity to the nucleotide sequence set forth in SEQ ID NO:5, wherein said nucleotide sequence having at least about 85% sequence identity to the nucleotide sequence set forth in SEQ ID NO:5 has Bt toxin binding activity;
- f) a nucleotide sequence having at least about 95% sequence identity to the nucleotide sequence set forth in SEQ ID NO:5, wherein said nucleotide sequence having at least about 95% sequence identity to the nucleotide sequence set forth in SEQ ID NO:5 has Bt toxin binding activity;
- g) a nucleotide sequence consisting of at least about 15 contiguous nucleotides of the nucleotide sequence set forth in SEQ ID NO:5;
- h) a nucleotide sequence that hybridizes under stringent conditions to the complement of the nucleotide sequence set forth in SEQ ID NO:5;
- and
- i) a nucleotide sequence complementary to at least one nucleotide sequence of a), b), c), d), e), f), g), or h).
7 more elements
Dependencies are inferred from the claim text.