Microelectrode recording analysis and visualization for improved target localization
AssigneesOregon Health & Science University, State of Oregon Acting By & Through the State Boar
InventorsJames McNames, Roberto Santiago, Jon Falkenberg, Kim Burchiel
Life of this patent
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Abstract
Methods of processing neuronal signals include processing microelectrode recordings (MERs) or portions of MERs to provide arrays of associated values, such as estimates of power spectral density, or a marginal probability distribution, or a rate of change of a spike rate. Such arrays of values can be displayed, and a classifier can be applied to, for example, aid in associating a MER with a particular brain feature.
Claims25
A method, comprising:
- selecting at least one microelectrode recording (MER);
- processing the at least one MER to obtain an associated array of values;
- and
- displaying the array of values.
An apparatus, comprising:
- a sampler configured to receive a microelectrode electrical signal (MES) and produce a sampled representation of the MES;
- a memory configured to store a series of values based on the sampled representation;
- and
- a processor configured to produce arrays of processed values based on the sampled representation and selected processing parameters.
A display method, comprising:
- receiving a plurality of microelectrode recordings associated with respective electrode insertion depths;
- producing an associated array of values for each recording;
- and
- displaying the associated array of values as a function of electrode insertion depth.
A method, comprising:
- receiving microelectrode recordings associated with respective insertion depths;
- and
- estimating a rate of change of spike rate based on the received microelectrode recordings.
An apparatus, comprising:
- an input configured to receive a plurality of microelectrode recordings;
- a processor configured to produce an estimate of a rate of change of spike rate as a function of insertion depth based on the microelectrode recordings.
A processing method, comprising:
- receiving a microelectrode recording;
- processing the microelectrode recording to produce an array of processed values;
- and
- associating the microelectrode recording with a particular brain region based on the processed values.
Dependencies are inferred from the claim text.