Real-time Elastic Registration to Determine Temporal Evolution of Internal Tissues for Image-Guided Interventions

A method for indicating disposition of moving target tissue in a living body, comprising:

• receiving first scan data representing a scan of a living body based at least in part on a first mode of measuring the living body with high spatial resolution at a first measurement time;
• receiving second scan data representing a scan of the living body based at least in part on a second mode of measuring the living body at a different second measurement time, wherein a moving target tissue in the living body changes from the first measurement time to the second measurement time in a way that is significantly different for treatment of the target tissue;
• determining an elastic transform that registers the first scan data elastically to the second scan data;
• and
• indicating a particular spatial arrangement of the moving target tissue in the living body at a particular time between the first measurement time and the second measurement time by interpolating the elastic transform.

An apparatus for indicating current disposition of moving target tissue in a living body, comprising:

• means for receiving high spatial resolution scan data representing a scan of a living body based at least in part on a first mode of measuring the living body with high spatial resolution, wherein a repeat rate for repeatedly obtaining the high spatial resolution scan data based on the first mode of measuring the living body over a period of time for treating the living body is limited to be no greater than a first repeat rate;
• means for receiving high temporal resolution scan data representing a scan of the living body based at least in part on a different second mode of measuring the living body over a second mode measurement duration, wherein a repeat rate for repeatedly obtaining the high temporal resolution scan data based on the second mode of measuring the living body over the period of time is greater than the first repeat rate;
• means for determining an elastic transform that registers the high spatial resolution scan data elastically to the high temporal resolution scan data;
• and
• means for indicating a current spatial arrangement of a moving target tissue in the living body during the second mode measurement time based on the elastic transform, wherein the moving target tissue changes over time among a plurality of spatial arrangements of the moving target tissue that are significantly different for treatment of the target tissue.

An apparatus for indicating disposition of moving target tissue in a living body, comprising:

• means for receiving first scan data representing a scan of a living body based at least in part on a first mode of measuring the living body with high spatial resolution at a first measurement time;
• means for receiving second scan data representing a scan of the living body based at least in part on a second mode of measuring the living body at a different second measurement time, wherein a moving target tissue in the living body changes from the first measurement time to the second measurement time in a way that is significantly different for treatment of the target tissue;
• means for determining an elastic transform that registers the first scan data elastically to the second scan data;
• and
• means for indicating a particular spatial arrangement of the moving target tissue in the living body at a particular time between the first measurement time and the second measurement time by interpolating the elastic transform.

A computer-readable medium carrying one or more sequences of instructions for indicating disposition of moving target tissue in a living body, wherein execution of the one or more sequences of instructions by one or more processors causes the one or more processors to perform the steps of:

• receiving high spatial resolution scan data representing a scan of a living body based at least in part on a first mode of measuring the living body with high spatial resolution, wherein a repeat rate for repeatedly obtaining the high spatial resolution scan data based on the first mode of measuring the living body over a period of time for treating the living body is limited to be no greater than a first repeat rate;
• receiving high temporal resolution scan data representing a scan of the living body based at least in part on a different second mode of measuring the living body over a second mode measurement duration, wherein a repeat rate for repeatedly obtaining the high temporal resolution scan data based on the second mode of measuring the living body over the period of time is greater than the first repeat rate;
• determining an elastic transform that registers the high spatial resolution scan data elastically to the high temporal resolution scan data;
• and
• indicating a current spatial arrangement of a moving target tissue in the living body during the second mode measurement duration based on the elastic transform, wherein the moving target tissue changes over time among a plurality of spatial arrangements of the moving target tissue that are significantly different for treatment of the target tissue.

A computer-readable medium carrying one or more sequences of instructions for indicating disposition of moving target tissue in a living body, wherein execution of the one or more sequences of instructions by one or more processors causes the one or more processors to perform the steps of:

• receiving first scan data representing a scan of a living body based at least in part on a first mode of measuring the living body with high spatial resolution at a first measurement time;
• receiving second scan data representing a scan of the living body based at least in part on a second mode of measuring the living body at a different second measurement time, wherein a moving target tissue in the living body changes from the first measurement time to the second measurement time in a way that is significantly different for treatment of the target tissue;
• determining an elastic transform that registers the first scan data elastically to the second scan data;
• and
• indicating a particular spatial arrangement of the moving target tissue in the living body at a particular time between the first measurement time and the second measurement time by interpolating the elastic transform.

An apparatus for indicating disposition of moving target tissue in a living body, comprising:

• a logic circuit configured for determining an elastic transform that registers a first scan elastically to a second scan in a time short compared to a duration for a first mode of measuring the living body;
• a processor;
• a computer readable medium carrying one or more sequences of instructions, wherein execution of the one or more sequences of instructions by the processor causes the processor to perform the steps of
• receiving high spatial resolution scan data representing a scan of a living body based at least in part on the first mode of measuring the living body with high spatial resolution, wherein a repeat rate for repeatedly obtaining the high spatial resolution scan data based on the first mode of measuring the living body over a period of time for treating the living body is limited to be no greater than a first repeat rate;
• receiving high temporal resolution scan data representing a scan of the living body based at least in part on a different second mode of measuring the living body over a second mode measurement duration, wherein a repeat rate for repeatedly obtaining the high temporal resolution scan data based on the second mode of measuring the living body over the period of time is greater than the first repeat rate;
• invoking the logic circuit for determining an elastic transform that registers the high spatial resolution scan data to the high temporal resolution scan data;
• and
• indicating a current spatial arrangement of a moving target tissue in the living body during the second mode measurement duration, wherein the moving target tissue changes over time among a plurality of spatial arrangements of the moving target tissue that are significantly different for treatment of the target tissue.

An apparatus for indicating disposition of moving target tissue in a living body, comprising:

• a logic circuit configured for determining an elastic transform that registers a first scan elastically to a second scan in a time short compared to a measurement duration for a first mode of measuring a living body;
• a processor;
• a computer readable medium carrying one or more sequences of instructions, wherein execution of the one or more sequences of instructions by the processor causes the processor to perform the steps of
• receiving first scan data representing a scan of a living body based at least in part on a first mode of measuring the living body with high spatial resolution at a first measurement time;
• receiving second scan data representing a scan of the living body based at least in part on a second mode of measuring the living body at a different second measurement time, wherein a moving target tissue in the living body changes from the first measurement time to the second measurement time in a way that is significantly different for treatment of the target tissue;
• invoking the logic circuit to determine an elastic transform that registers the first scan data elastically to the second scan data;
• and
• indicating a particular spatial arrangement of the moving target tissue in the living body at a particular time between the first measurement time and the second measurement time by interpolating the elastic transform.