Image acquisition and reconstruction method for functional magnetic resonance imaging
AssigneeWisconsin Alumni Research Foundation
InventorsCharles Mistretta, Walter Block
Life of this patent
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Abstract
Acquisition of MR data during a fMRI study employs a hybrid PR pulse sequence to acquire projection views from which multi-slice image frames may be reconstructed that depict the BOLD response to an applied stimulus or performed task. Composite images are reconstructed at each slice using the combined interleaved projection views from all the acquired image frames. The composite images are used to reconstruct the highly undersampled image frames.
Claims12
A method for producing an image of a subject's brain positioned in a field of view (FOV) of a magnetic resonance imaging (MRI) system, the steps comprising:
- a) acquiring with the MRI system a set of projection views at each of a plurality of intervals following an event that produces brain activity in the subject;
- b) producing a composite image with projection views acquired during the plurality intervals wherein the projection views are interleaved with each other;
- c) reconstructing an image frame at each interval by:
- c)i) backprojecting a set of projection views acquired at the interval into the FOV and weighting the value backprojected into each image pixel by the value of the corresponding pixel in the composite image;
- and
- c)ii) summing the backprojected values for each image pixel.
A method for producing an image of a subject positioned in a field of view (FOV of a magnetic resonance imaging (MRI) system, the steps comprising:
- a) acquiring with the MRI system a set of views of the subject's brain at a plurality of intervals following an event that produces brain activity;
- b) reconstructing a composite image with projection views acquired at a plurality of intervals in step a), wherein said projection views used to form the composite image are interleaved;
- and
- c) reconstructing an image frame at each interval by:
- c)i) producing an image data set from projection views acquired in step a) during the interval;
- and
- c)ii) producing an image frame of the subject's brain using the image data set and weighting each image pixel location by the corresponding pixel value in the composite image.
Dependencies are inferred from the claim text.