Biomarkers for sensitivity of proliferative diseases to mtor inhibitors
OwnerAnne Boulay, Heidi Lane +2inventors
InventorsAnne Boulay, Heidi Lane, Sauveur-Michel Maira, Terence O'Reilly
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Abstract
Disclosed is a method for determining the sensitivity of a proliferate disease in a subject to treatment with an mTOR inhibitor, comprising determining the level of expression and/or phosphorylation state of S6 in a sample derived from the subject, as well as related methods of treatment and uses.
Claims10
1-4. (canceled)
A method for determining the sensitivity of a proliferative disease in a subject to treatment with an mTOR inhibitor, comprising determining the level of expression and/or phosphorylation state of S6 in a sample derived from the subject.
A method according to 5, wherein the sample is derived from a tumor in the subject.
Dependencies are inferred from the claim text.