Novel antibacterial agents

A compound represented by formula (I):

• their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, and their pharmaceutically acceptable salts, wherein:
• Z1 represents O or S;
• Z2 represents O or S;
• R1 represents a substituent selected from the group consisting of:
• a halogen group,
• an azido group,
• a nitro group,
• a cyano group,
• XR6, where:
• X represents O or S;
• and
• R6 represents a substituent selected from the group consisting of:
• hydrogen,
• formyl, and
• a substituted or unsubstituted group selected from the group consisting of (C1-C6)alkyl, cycloalkyl, aryl, aralkyl, acyl, thio acyl, heterocyclyl, heteroaryl, alkylsulfonyl, arylsulfonyl, and aralkylsulfonyl;
• N(R7aR7b) where:
• R7a and R7b each independently represent a substituent selected from the group consisting of:
• hydrogen,
• a formyl group,
• a substituted or unsubstituted group selected from the group consisting of (C1-C6)alkyl, aryl, aralkyl, heteroaryl, heteroaralkyl, and an aminoacid residue which is attached through an acid moiety, or
• R7a and R7b together with nitrogen represents a mono or bicyclic saturated or unsaturated ring system which may contain one or more heteroatoms selected from O, S or N;
• a formula —NHC(═Y)R8 wherein:
• Y represents O or S;
• and
• R8 is a hydrogen atom or a substituted or unsubstituted substituent selected from the group consisting of a (C1-C6)alkyl group, a (C1-C6)alkoxy group, an aryl group, a (C3-C6)cycloalkyl group, an amino group, a monoalkylamino group, a dialkylamino group, a cycloalkylamino group, an arylamino group, an aroylamino group, an alkylcarbonylamino group, an arylcarbonylamino group, a heteroaryl group, a heterocyclyl group, a heteroaralkyl group, and a heteroaroylamino group;
• and
• a formula selected from the group consisting of:
• —NHS(O)p(C1-C4)alkyl,
• —NHS(O)p(C1-C4)aryl, and
• —NHS(O)p(C1-C4)heteroaryl,
• where p is 0 to 2;
• R2 and R3 are the same or different and independently represent a hydrogen, a halogen, a hydroxy group, an alkyl group, or an alkoxy group;
• R4 and R5 are the same or different and independently represent a hydrogen, a cyano group, a nitro group, an amino group, a halogen, a hydroxyl group, or a substituted or unsubstituted group selected from the group consisting of (C1-C6)alkyl, haloalkyl, (C1-C6)alkoxy, (C1-C6)alkylthio, (C3-C6)cycloalkyl, or either of R4 or R5 represent an oxo or thiooxo group;
• n is 0, 1, or 2;
• when Z2 represents S, A represents a substituent selected from the group consisting of:
• NHR9, where R9 represents hydrogen or a substituted or unsubstituted group selected from the group consisting of alkyl, aryl, alkoxy, alkenyl, cycloalkyl, heteroaryl, and heterocyclyl groups;
• a substituted or unsubstituted cycloalkyl group;
• a substituted or unsubstituted aryl group;
• a substituted or unsubstituted five to seven membered heteroaryl group;
• a substituted or unsubstituted heterocyclyl group wherein the heterocycle is attached through a carbon atom;
• a substituted or unsubstituted heteroarylalkenyl group;
• and
• a substituted or unsubstituted heterocyclylalkenyl group;
• when Z2 represents O, A represents NHR9, where R9 represents a phenyl group substituted by a nitro group or a substituted or unsubstituted groups selected from the group consisting of alkoxy, alkenyl, cycloalkyl, heteroaryl, and heterocyclyl groups;
• m is an integer in the range of 0 to 2;
• and
• n is an integer ranging from 0-4, wherein when n is 0, R9 does not represent hydrogen or an alkyl group.