Remedy for spinal canal stenosis
OwnerYoshifumi Takenobu, Yoshihisa Kamanaka +1inventors
InventorsYoshifumi Takenobu, Yoshihisa Kamanaka, Takaaki Obata
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Abstract
A remedy for spinal canal stenosis which comprises a combination of a compound having EP2 agonism with a compound having EP3 agonism. A drug comprising a combination of a compound having EP2 agonism with a compound having EP3 agonism shows an efficacy in a rat gait disorder model induced by compression of cauda equina. Namely, it is efficacious against spinal canal stenosis to use a combination of a compound having EP2 agonism with a compound having EP3 agonism or a compound having both EP2 agonism and EP3 agonism.
Claims15
An agent for preventing and/or treating spinal canal stenosis which comprises a combination of a compound having EP2 agonist action and a compound having EP3 agonist action.
An agent for preventing and/or treating spinal canal stenosis which comprises a compound having EP2 agonist action and EP3 agonist action.
A method for preventing and/or treating spinal canal stenosis in a mammal, which comprises administering to a mammal an effective amount of a compound having EP2 agonist action and a compound having EP3 agonist action, or a compound having EP2 agonist action and EP3 agonist action.
(canceled)
Dependencies are inferred from the claim text.