Back to results
US 2007/0167357 A1Published application
Dab9 DERIVATIVES OF LIPOPEPTIDE ANTIBIOTICS AND METHODS OF MAKING AND USING THE SAME
AssigneeMigenix Inc.
InventorsMaria Fardis, Dale Cameron, Vincent Boyd
Life of this patent
Estimating the term…
Abstract
The present invention provides Dab9 derivatives of amphomycin-type lipopepetide antibiotics that display antimicrobial activity against Gram-positive bacteria, methods and intermediates for synthesizing the compounds and methods of using the compounds in a variety of contexts, including in the treatment and prevention of infections.
Claims17
An antimicrobial compound according to structural formula (III):
- including the salts thereof, wherein:
- R1 is a linear or branched, saturated or singly or multiply unsaturated alkyl or hydroxy alkyl having a chain comprising from 6 to 22 carbon atoms;
- R2 is OH or NH2;
- and
- R6 is a substitutent which includes a primary or secondary amine.
2 more elements
Dependencies are inferred from the claim text.