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US 2007/0166746 A1Published application
Human cytokine receptor
AssigneeZymoGenetics, Inc.
InventorsScott Presnell, Wenfeng Xu, Wayne Kindsvogel, Zhi Chen
Life of this patent
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Abstract
Cytokines and their receptors have proven usefulness in both basic research and as therapeutics. The present invention provides a new human cytokine receptor designated as “Zcytor16.”
Claims2
A method for detecting a genetic abnormality in a patient, comprising:
- obtaining a genetic sample from the patient;
- producing a first reaction product by incubating the genetic sample with a polynucleotide comprising at least 14 contiguous nucleotides of SEQ ID NO:1 or the complement of SEQ ID NO:1, under conditions wherein said polynucleotide will hybridize to complementary polynucleotide sequence;
- visualizing the first reaction product;
- and
- comparing said first reaction product to a control reaction product from a wild type patient, wherein a difference between said first reaction product and said control reaction product is indicative of a genetic abnormality in the patient.
2 more elements
A method for detecting a cancer in a patient, comprising:
- obtaining a tissue or biological sample from the patient;
- labeling a polynucleotide comprising at least 14 contiguous nucleotides of SEQ ID NO:1 or the complement of SEQ ID NO:1;
- incubating the tissue or biological sample under conditions wherein the polynucleotide will hybridize to complementary polynucleotide sequence;
- visualizing the labeled polynucleotide in the tissue or biological sample;
- and
- comparing the level of labeled polynucleotide hybridization in the tissue or biological sample from the patient to a normal control tissue or biological sample,
- wherein an increase in the labeled polynucleotide hybridization to the patient tissue or biological sample relative to the normal control tissue or biological sample is indicative of a cancer in the patient.
4 more elements
Dependencies are inferred from the claim text.